Begin  The Authors
 Introduction

Tropical Diseases:

I Leishmaniasis
II Paracoccidioidomycosis
III Blastomycocis
IV Chromoblastomycosis
V Lepra
VI Sporotrichosis
VII Histoplasmosis
VIII Rhinosporidiosis
IX Mycetomas
X Rhinoscleroma
XI Chagasdisease
XII Actinomycosis
XIII Mucormycosis
XIV Amoebiasis
XV Protothecosis
XVI Lobomycosis
XVII Phaeohyphomycosis
XVIII Pruritus actinicus
XIX Bite of snake
XX Coccidioidomycosis

 List of cases

 References
 Contact

XVIII. Actinic Pruritus

Case 68: Actinic Pruritus / Staphylococcal scalded skin syndrome

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Actinic Pruritus

Staphylococcal scalded skin syndrome

Click here to see the picture 68-A1
Fig.68-A1
Actinic Pruritus

In a 8-year old boy from the flatlands around the Apure river, the so called "Llanos occidentales" developed in the course of several weeks eztensive papulous-vesicular, very itching skin alterations. Especially the forehead, the environs of both eyes, the skin above the cheek bones and the nose were affected. The chin was less affected, but both ears showed vesicular-papillomatous skin lesions. A pharmacodermatitis could be excluded.

Click here to see the picture 68-B1
Fig.68-B1
Staphylococcal scalded skin syndrome

Another 8-years old boy felt ill suddenly with high fever, loss of appetite and somnolencia, accompanied by skin lesions, especially in the face. They consisted of superficial blisters whch scaled of easily from the base. They were found mainly on the forehead, the environs of the left eye, the perioral region and the ears.

Click here to see the picture 68-A2
Fig.68-A2
Actinic Pruritus

Histologically there was a diffuse hyperkeratoris of the epidermis. The corium showed an oedema and dense round cell perivascular infiltrates.

Click here to see the picture 68-B2
Fig.68-B2
Staphylococcal scalded skin syndrome

Histologically the intraepithelial blister formation containing fibrine and leucocytes could be observed.

Click here to see the picture 68-A3
Fig.68-A3
Actinic Pruritus

With high power the dense perivascular infiltrates and the oedema are good to see.

Click here to see the picture 68-B3
Fig.68-B3
Staphylococcal scalded skin syndrome

With higher power numerous inflammatory elements could be recognized, mostly leucocytes, masses of fibrine and several acantholytic epithelial cells.

Click here to see the picture 68-A4
Fig.68-A4
Actinic Pruritus

After the treatment with chloroquine and cortisone the papulous skin lesions transformed into elevated, dark red, and firm plaques which later healed completely.

Click here to see the picture 68-B4
Fig.68-B4
Staphylococcal scalded skin syndrome

Occasionally an intraepithelial blister formation is seen with an exsudate and several acantholytic epithelial cells. The disease is called "Staphylococcal scalded skin syndrome" or "Lyell syndrome".


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Facultad de Medicina
Universidad de Los Andes
Merida - Venezuela