In a 8-year old boy from the flatlands around the Apure river, the so called "Llanos occidentales" developed in the course of several weeks eztensive papulous-vesicular, very itching skin alterations. Especially the forehead, the environs of both eyes, the skin above the cheek bones and the nose were affected. The chin was less affected, but both ears showed vesicular-papillomatous skin lesions. A pharmacodermatitis could be excluded.